First in Class Solutions

Cumberland Biotherapeutics, Inc. is committed to science and Ayurvedic medicine, conducting research and drug development creating bioceutical medicines that can benefit the lives of patients.

DENTOCLUDE F

Infection Control

Micro-leakage in dentistry refers to the seepage of fluids, bacteria, and molecules through tiny gaps or spaces at the interface between a dental restoration (such as a filling or crown) and the natural tooth structure. This phenomenon can lead to secondary decay, compromised pulp vitality, and is a major contributor to tooth sensitivity after dental procedures. Micro-leakage is often triggered by improper bonding, inadequate preparation, material shrinkage, and natural wear over time.

DENTOCLUDE F

Investors

“DentoClude F represents the kind of innovation investors dream of being early to—where sound science meets human transformation. Each restored smile isn’t just dentistry; it’s validation that regeneration is possible. This is not a product chasing a market—it’s a movement redefining what dental restoration means. Early investors aren’t simply funding growth; they’re shaping the standard of oral health for decades to come.”

DENTOCLUDE F

Instructions

The DentoClude F usage video provides clear, step-by-step instructions for dental professionals administering the product to patients experiencing tooth sensitivity and pain. It demonstrates proper application techniques, including opening the DentoClude F packaging, using an applicator to dispense the product, and precisely applying it to targeted tooth surfaces—especially those exhibiting hypersensitivity. The video emphasizes patient comfort, clean application, and following all safety and hygiene protocols to ensure optimal product performance.

Patient & Practice Questions    
    
Components of DentoClude F    
    
Benefits to Practitioners    
    
3 Simple Questions    
    
DentoClude F goes beyond just protecting your smile—it supports whole-body wellness by maintaining a healthy balance of over 770 beneficial bacteria in your mouth. According to the article “The Bacterial Connection between the Oral Cavity and Gut Diseases,” oral bacteria can travel from the mouth to the gut and may contribute to serious conditions like irritable bowel syndrome, inflammatory bowel disease, and colorectal cancer if harmful types are not kept in check. By helping to reduce pathogenic bacteria and promote a strong, diverse oral microbiome, DentoClude F acts as your first line of defense, supporting both oral and digestive health for lasting well-being. Download Article

DENTOCLUDE F

Practice Solutions

DentoClude™ F with fluoride is intended to be used in the manner based on indications for use. DentoClude™ F contains Bioactive Glass with particle size of less than 1μm as the key ingredient designed to fill and block the dentin tubules. DentoClude™ F Tubule Agent should be used during the restoration of teeth. DentoClude™ F is applied to the exposed dentin and the solvent evaporated off, leaving the bioactive glass. DentoClude™ F is manufactured in such a way that it is intended to enter the exposed dentin tubules and penetrate to a greater depth that prevents microleakage and sensitivity. In addition, Bioactive Glass in studies suggests having an anti-inflammatory effect

Practice & Patient Solutions

DentoClude F

DentoClude™ F, we innovate dental solutions to enhance patient care. Our flagship product, DentoClude™ F, offers cutting-edge technology for effective tooth sensitivity relief. CBT’s products improve patients’ lives. US Federal Law restricts this device to sales by or on the order of a LICENSED Dental Professional DentoClude™ F Dentin Tubule Agents

Global Reach

USA HQ
1565 Jackson Point Road, Sewanee, Tennessee 37375

India HQ
D.No.8-2-231/70 to 73, Ground Floor, EVK Complex, Krishna Nagar Cross Road Junction, Jubilee Hills, Hyderabad-500045, India

LigoFlex Solution

LigoFlex Capsule, a drug-free joint health dietary supplement that reduces inflammation, muscle aches and joint pain.
Pure Relief, Real Results “LigoFlex Capsules have been a game-changer for my arthritis pain. After a couple of weeks, the inflammation and joint stiffness noticeably decreased, and I regained much of my mobility.”

Cumberland Biotherapeutics developed DentoClude F® technology with bioactive glass with Fluoride, particle size of <1 µm that contains botanicals with anti-infective & anti-inflammatory active extracts. DentoClude F® is approved by the US FDA, USA and DCGI/ AYUSH, India. DentoClude F® is  available only through your Dental Provider. DentoClude F®, a NOVEL device with Bioactive Glass that blocks dentin tubules and prevents micro-leakage resulting in a decrease in sensitivity at root surface exposed due to periodontal disease or post periodontal therapy as well as periodontal and implant bone regeneration. 

Know Our Story

Inspired Solutions for a Balanced Life

Driven by passion and purpose, we are here to redefine the healthcare industry with innovative solutions that put people first.

LigoFlex

Pure Relief, Real Results

Pure Relief, Real Results –
“LigoFlex Capsules have been a game-changer for my arthritis pain. After a couple of weeks, the inflammation and joint stiffness noticeably decreased, and I regained much of my mobility.”

“Taking LigoFlex capsules daily has reduced the swelling and pain in my joints. The natural ingredients seem to work well together, and I appreciate that it supports cartilage health while easing inflammation.”

LigoFlex ES capsules consist of bioactive botanical extracts used in treatment of a variety of inflammatory diseases such as rheumatoid arthritis and osteoarthritis.

2025

Contact Us

Cumberland Biotherapeutics, Inc. is a privately held corporation, located on the Cumberland Plateau near Sewanee, Tennessee. CBT is a biopharmaceutical company that develops and commercializes various forms of therapeutics to treat diseases for unmet medical needs of patients and their families.

Reach us through

Send us a Message or Request Units

© 2025 Cumberland Bio All Rights Reserved.

Translate »